E-HYBENX-SYRINGES-2x1ML

HybenX Oral Tissue Decontaminant 2 × 1 mL Syringes

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Oral Tissue Decontaminant

Variations
Clear

Targets the Trigger of Periodontal Disease by Eliminating Bacteria on Contact

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Includes: 2 x 1 mL HybenX syringe (Gel or Liquid) + 2 x syringe tips
SKU:
E-HYBENX-SYRINGES-2x1ML-LIQUID
E-HYBENX-SYRINGES-2x1ML-GEL

SKU: E-HYBENX-SYRINGES-2x1ML Categories: , Tag: Brand:

Mechanism of action

When biofilm and periodontal pathogens become desiccated, they are no longer able to function as a biofilm, and can be easily removed from oral structures with a rinse. HybenX® is a professionally applied gel that utilizes an electrostatic charge to attract water from the pathogens associated with inflamed or infected oral tissues. This electrostatic action, known as Desiccation Shock Technology (DST), dries out microbial pathogens, their protective biofilm, and necrotic tissue, rendering them harmless and easy to remove. The instantaneous and complete removal of periodontal pathogens helps calm inflammatory mediators quickly, safely, and effectively, speeding up the natural healing process. HybenX® contains sulfonated phenols, making it easy to use. Apply and rinse this non-antibiotic, non-systemic solution for oral decontamination above and below the gingiva.

Benefits

  • Eradicates bacteria, biofilm, and necrotic tissue
  • Inhibits infectious and inflammatory disease processes
  • Single treatment transitions from infected to a healing state
  • Hemostatic
  • Non-systemic and antibiotic-free

Favorite features

  • Instant results
  • Significantly softens calculus
  • Easy 10–30 second application
  • Cost-effective: Not just for a single site but for the whole mouth
  • Reduced bleeding during scaling and root planing
  • High viscosity (at room temperature) for easy application, low viscosity (at body temperature) for easy rinsing
  • Does not harm healthy tissues
  • Safe on enamel, dentin, titanium and restorative materials

Main ingredient

Sulfonated phenols

Package includes

  • 2 × 1 mL syringe (available in gel or liquid)
  • 2 × blue supragingival tips
  • 2 × clear subgingival tips

Periodontal therapy application

The interproximal placement of applicator tip to apply HybenX®
Interproximal dispensing of HybenX®
The appearance of gingival tissue after placement and rinsing of HybenX® product
Rinsing HybenX® after the required 30 seconds for healing processes to work

The Science Behind HybenX®

HybenX®Local antibiotics (Minocycline or other)Systemic antibiotics (Various)
Main ingredientLocal sulphonated phenolicVarious ingested systemic antibiotics
Cost per patient1 syringe ≅ 1 arch ≅ $501 syringe ≅ 1 tooth ≅ $30Dependent on drug
IndicationDysbiotic sites as evidenced by BOP, deposits or inflammationPeriodontal pockets ≥ 5mmPotential short term value in acute infection, very low certainty for long term follow-up1
Targets all periodontal pathogens in 10–30 sec.YesNoNo
Effect on calculusSoftens calculusNoneNone
Post op instructionsNoneEating and oral hygiene restrictions for 7–10 daysUse drugs to completion and do not miss doses
Contribution to global antimicrobial resistanceNoNoOverprescription of antibiotics globally increasing resistance
ContraindicationsSulfur allergyMinocycline allergy and various health conditionsVarious AB allergies

Conclusion from randomized, controlled clinical trial

“SRP plus the desiccant resulted in a greater reduction in clinical, microbial and inflammatory mediators compared to SRP alone.” (red complex bacteria)2

Red complex bacteria (T. forsythia, P. gingivalis, T. denticola) mean counts (×10⁵) in SRP + HybenX vs. SRP alone at baseline, 30 days and 365 days. Adapted from the Isola study.

Tooth surface plaque before and after HybenX® 30 seconds application

Suggested directions for use

Peri-implants adjunctive soft tissue cleanser

  1. Isolate and dry the implant
  2. Apply HybenX® via cannula around the implant
  3. Wait 10–30 seconds
  4. Remove HybenX® with high volume suction and rinse with water until clear

Caries and crown preparation cleanser

  1. Isolate and dry the tooth
  2. Apply HybenX® via cannula into the cavity preparation or around the crown preparation
  3. Wait 10–30 seconds
  4. Remove HybenX® with high volume suction and rinse with water until clear

Root canal cleanser

  1. Isolate and dry the canals
  2. Apply HybenX® into the deepest portion of the canals using the cannula, irrigating up to the top of the access cavity
  3. Distribute using an endodontic reamer to work the HybenX® into the canals
  4. Wait up to 60 seconds
  5. Remove HybenX® with high volume suction and rinse with water until clear

Periodontal adjunctive debridement cleanser

  1. Dry the tooth
  2. Apply HybenX® via cannula pre & post scaling and root planing where required. Supragingival and subgingival to the base of periodontal pockets
  3. Wait 10–30 seconds
  4. Remove HybenX® with suction and rinse with water until clear

References

  1. Khattri S, Kumbargere Nagraj S, Arora A, Eachempati P, Kusum CK, Bhat KG, Johnson TM, Lodi G. Adjunctive systemic antimicrobials for the non-surgical treatment of periodontitis. Cochrane Database of Systematic Reviews 2020, Issue 11.
  2. Isola, G., Matarese, G., Williams, R.C. et al. The effects of a desiccant agent in the treatment of chronic periodontitis: a randomized, controlled clinical trial, 2017.

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