An ingredient patented by Oral Science
Citrox®
A plant-based bioflavonoid complex, patented by Oral Science and found in X-PUR Opti-Rinse Plus, X-PUR Cariø Plus and X-PUR GummiZ, to support antimicrobial, antiviral, antifungal and anti-inflammatory oral care.
Plant-based origin
Bioflavonoids derived from bitter oranges
Naturally derived. Biodegradable, eco-friendly, non-toxic, hypoallergenic and alcohol-free.
Patented formulation
Organic acids + bioflavonoid complex
A unique combination patented by Oral Science to support antimicrobial, antiviral and antifungal oral protection.
Derived from nature
The gift of the bitter orange
Citrox® is extracted from the bitter orange — an ancestral plant whose bioflavonoids and organic acids Oral Science has refined to create a precisely engineered, patented antimicrobial complex.
Plant-based protection
Bioflavonoids + organic acids
derived from bitter oranges
How Citrox® works
- Citrox®’s bioflavonoids bind to bacterial cell walls and interfere with the proteins microorganisms need to survive.
- It is designed to provide antimicrobial, antiviral and antifungal support in oral care formulations.
- It strengthens the protective role of X-PUR Opti-Rinse Plus, X-PUR Cariø Plus and X-PUR GummiZ when combined with complementary actives such as sodium fluoride, xylitol and CPC.
- It supports the care of patients concerned with dental plaque, gingivitis, caries risk and xerostomia.
Citrox® in action
1. Binds to bacteria
Bioflavonoids attach to bacterial cell walls in the oral environment.
A targeted, plant-based first line of action.
2. Disrupts proteins
Interferes with the proteins microorganisms need to survive.
Antimicrobial, antiviral and antifungal support.
3. Strengthens the formula
Acts in synergy with sodium fluoride, xylitol and CPC.
A modern approach to managing plaque, gingivitis and caries risk.
A synergistic 4-component formula
X-PUR Opti-Rinse Plus combines Citrox® with xylitol, CPC and sodium fluoride to support the prevention of plaque and gingivitis, enamel remineralization and caries risk management. Citrox® is also found in X-PUR Cariø Plus and X-PUR GummiZ, within the X-PUR® line.
| Ingredient | Role | What it helps address |
|---|---|---|
| Citrox® | Antimicrobial bioflavonoid complex | Dental plaque, gingivitis, general microbial control |
| Xylitol | Anti-cariogenic sugar alcohol | Reduces cariogenic bacterial activity |
| CPC | Cetylpyridinium chloride | Antimicrobial support against gingivitis |
| Sodium fluoride (NaF) | Remineralizing fluoride | Enamel remineralization and caries prevention |
Citrox® is present throughout the X-PUR® line — see product references below.
Key benefits
Why clinicians choose Citrox®
Antimicrobial
Helps reduce harmful microorganisms in the mouth.
Antiviral and antifungal
Designed to support broader microbial control in oral care formulations.
Anti-inflammatory support
Helps patients manage gingival inflammation.
Clean profile
Biodegradable, eco-friendly, non-toxic, hypoallergenic and alcohol-free.
Why it matters for patients
A modern, patient-friendly approach to everyday oral care — from daily comfort to long-term protection.
Daily patient experience
- Alcohol-free and pH-neutral for a gentler daily rinse.
- Helps prevent or reduce dental plaque and gingivitis.
- Helps remineralize tooth enamel and supports caries prevention.
Clinical applications
- Caries risk management.
- Periodontal and peri-implant support.
- Orthodontic patients.
- Management of dental sensitivity and xerostomia.
Citrox® throughout the X-PUR® line
A patient-friendly approach to managing plaque, gingivitis and caries risk — available in X-PUR Opti-Rinse Plus, X-PUR Cariø Plus and X-PUR GummiZ, all patented by Oral Science.
See products with Citrox®Products containing Citrox®
