X-PUR CariØ Plus Toothpaste 100 g

Name: X-PUR CariØ Plus Toothpaste 100 g - Oral Science
SKU: XP-CARI0-100G
Price: 7.99 CAD
Availability: InStock

25% Xylitol & CITROX® Toothpaste

Unique and Proven Formulation to Reduce Cariogenic Bacteria and Lesions

Includes: 100 G tube (Spearmint or Bubble Gum Flavor)

NPN: 80087491

SKU:

XP-CARI0-JUNIOR

XP-CARIO

SKU: XP-CARI0-100G Categories: Babies & Children, CITROX®, Home-Care, Toothpastes & Gels Brand: X-PUR CariØ Plus, X-PUR®

Mechanism of action

X-PUR CariØ^® Plus contains a scientifically proven 25% medicinal-grade xylitol formulation, which effectively reduces the cariogenic bacteria load during the colonization and adhesion stages of the caries process. Numerous studies have demonstrated that tooth decay-causing bacteria are unable to metabolize xylitol. This leads to a reduction in lactic acid and polysaccharide production, making X-PUR CariØ^® Plus highly effective in preventing the caries process. Additionally, it can reduce both non-cavitated and cavitated lesions and promote remineralization.

25% Xylitol

Reduces cariogenic bacteria load

Cariogenic microorganisms cannot metabolize xylitol, which results in their inability to produce lactic acid or polysaccharide which causes caries.

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CITROX®

Antimicrobial patented complex

Plant-based biodegradable bioflavonoid complex offering a powerful antibacterial, antifungal, antiviral, antioxidant and anti-inflammatory effect.

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Benefits

Affordable

Complements topical fluorides by reducing cariogenic bacteria load

Effective against acute otitis media

Fluoride-free

Gentle formulation

Gluten-free

GMO-free

Low abrasiveness (RDA level of 60)

Sodium lauryl sulfate free

Natural health product

Neutral pH of 7.01

Safe for the environment: does not contain plastic particles that could harm the environment

Scientifically proven formulation

Unique patented formulation with CITROX^®: specific antibacterial bioflavonoid complex

Ideal for

Adults

Children and toddlers

Disabled patients

Dysphagic patients

Fluoride-free lovers

Daycare

Disadvantaged population

Elderly people

Holistic lifestyle patients

Pregnant women

Public health

Vegetarians & vegans

Directions for use

At least twice a day, for a minimum of three months¹

Brush with a film of toothpaste. Expectorate. For optimal results, do not eat, drink or rinse for 30 minutes.

Study against cavities

Comparatively to a fluoride toothpaste, X-PUR CariØ^® Plus produces²:

60% less non-cavitated lesions
80% less cavities
40% more remineralized lesions

Average lesions of 201 Kosovar children brushing 2 times per day over 2 years

	Control fluoride toothpaste	X-PUR CariØ®
60% less non-cavitated lesions	6.4	2.6
80% less cavities	3.6	0.7
40% more remineralized lesions	1.9	2.7

Reduces cariogenic bacteria load of highly infected patients

Patients studied	Before using X-PUR CariØ®	After using X-PUR CariØ®
102 children aged 6 months–2 years after 2 years of brushing³	28% without Streptococcus Mutans 17% highly infected	45% without Streptococcus Mutans 5% highly infected
43 adults after 3 months of brushing⁴	0% without Streptococcus Mutans and Lactobacillus 34% highly infected	24% without Streptococcus Mutans and Lactobacillus 0.3% highly infected
36 schoolchildren in 3 groups brushing for 1, 2 or 3 months	—	Reduction of bacteria load after 3 months. Results were maintained even 6 months after stopping using X-PUR CariØ®

More than 12 years of research proving its efficacy

Since 1952, fluoride has been the most widely used therapeutic agent in toothpaste. However, for patients highly infected by cariogenic bacteria (100,000 Streptococcus mutans/mL of saliva), which represents a significant percentage of your patients, fluoride toothpaste may not offer optimal removal of cariogenic bacteria, despite its remineralization properties.

Dr. Jacques Véronneau, a clinician, researcher, and cariologist in Canada, began his journey more than 12 years ago to find an effective therapeutic agent to reduce the cariogenic bacteria load. His research included conducting studies with 99 Kosovar children to evaluate the efficacy of a 25% xylitol toothpaste against cariogenic bacteria.

The results were conclusive, leading Oral Science to launch the first Canadian 25% medicinal-grade xylitol toothpaste.

Clinical observations on periodontitis

Medical treatment of periodontal disease requires the identification of the pathological activity threshold of bacteria. An explanatory study of nine high-risk patients using X-PUR CariØ^® Plus showed a 78% reduction of these bacteria after brushing for three months.⁵

References

Oana Chi, Msc(c), Jacques E. Veronneau, DMD, PhD, Mindra Badea, DMD, MSc. Mcgill University, Canada; University, Romania. The Minimal and Sustainable Timeframe for an Antibacterial Effects of Xylitol 25% Toothpaste: Observational Design Documenting. ↩︎
Jacques E. Veronneau, DMD, PhD, Blerta Laiti-Xhemaji, PhD, Adim Begzati, DMD, MSc. McGill University, Canada; Prishtina University, Kosovo. RCT Testing The Efficacy of Natural Toothpaste on the Control of Carious Process: A New Era of Therapeutic Efficacy in Primary Prevention. ↩︎
Latifi-Xhemajli B, Kutllovci T, Begzati A, Rexhepi A, Ahmeti D. A Prospective Longitudinal Cohort Study of the Effectiveness of 25% Xylitol Toothpaste on Mutans Streptococci in High Caries-Risk Young Children. Eur J Paediatr Dent. 2023 Sep 1;24(3):188-193. doi: 10.23804/ejpd.2023.1731. PMID: 37668463. ↩︎
Blerta Laiti-Xhemaji, PhD, Jacques E. Veronneau, DMD, PhD, Adim Begzati, DMD, MSc., McGill University, Canada; Prishtina University, Kosovo. Observational Designs Testing the Antibacterial Effects of Natural Toothpaste on Cariogenic Bacteria. ↩︎
Clinical observations of Dr. Jacques Véronneau, 2021. ↩︎