Papacárie Duo 1 mL Syringe
$194.99
Papain Caries Removal Gel
Softens and Detaches Caries from Healthy Dentin or Enamel in 30 Seconds without Pain, Anesthesia or Drilling
| Quantity | Unit price |
|---|---|
| 1+ | $194.99 |
| 3+ | $179.99 |
Mechanism of action
Papacárie Duo® is an enzyme-based gel specially designed for the atraumatic caries removal without anesthesia that does not contain toxic or irritating components.
A single drop softens caries and allows it to be removed from healthy dentin with a simple curette or spoon excavator. It only reacts in contact with infected dentin, leaving the healthy tissue intact.
In just 30 seconds, without pain or tenderness, you can remove cavities using only a hand instrument. In most cases, there is no need for anesthesia and/or drill.
Ingredients
Papain
Medicinal ingredientProteolytic enzyme derived from papaya fruit that break down carious dentin without affecting healthy teeth.
Non-medicinal ingredients: Polyethylene Glycol, Ammonium Chloride, C.II. 74160.
Indications
Softens caries-damaged infected dentin to ease removal by a dental professional
Aid in the physical removal of caries without the use of drilling
Benefits
Pain-free
Doesn’t require anesthesia
Reduced patient anxiety
Less mechanical removal needed
Quick process
30–60 seconds (repeat as needed
Versatile
Can be used in primary and permanent dentition
Safe and harmless
No toxic or irritating components
Easy application
30–60 seconds (repeat as needed
Directions for use
Adults & children 2 years and older
0.1–3 mL, 1 time per day. To be used by a dental professional.




Repeat process until all damaged dentin is removed (confirmed by no softening occurring).
Over 15 Years of Clinical Evidence
Papacárie Duo® is an effective product for CMCR on occlusal dentinal tissue in deciduous teeth, demonstrating a high clinical and radiographic success rate after 12 months of follow-up.1
Papacárie Duo® has similar antibacterial efficacy against cariogenic flora as chemomechanical caries removal agents.2
Papacárie Duo® was found to be conservative in caries removal. Papacárie Duo® was more efficient in removing bacteria in lesser time from the infected carious lesion.3





Testimonials
“I’m absolutely happy with Papacárie Duo®, I just remove infected dentin leaving 100% of healthy tissue there. It’s very gentle with patients and makes the caries treatment calm and easy.”
“Papacárie Duo® is very useful in patients with fear of needles and drill! Without a doubt I repeat!”

“I have used it with children and I really liked it. I will certainly repeat and use it also in adult patients.”
“I have used it with children and is very effective and comfortable. It makes my cavity treatment very gentle”

References
- Bussadori, Sandra Kalil et al. Chemo-mechanical caries removal with Papacárie Duo®: case series with 84 reports and 12 months of follow-up. The journal of contemporary dental practice vol. 15,2 250-3. 1 Mar. 2014, doi:10.5005/jp-journals-10024-1523 ↩︎
- Reddy, Maram Vinay Chand et al. Efficacy of antimicrobial property of two commercially available chemomechanical caries removal agents (Carisolv and Papacárie Duo®): An ex vivo study. Journal of International Society of Preventive & Community Dentistry vol. 5,3 (2015): 183-9. doi:10.4103/2231-0762.159955 ↩︎
- Sahana, Suzan et al. Effectiveness of chemomechanical caries removal agents Papacárie Duo® and Carie-Care™ in primary molars: An in vitro study. Journal of International Society of Preventive & Community Dentistry vol. 6,Suppl 1 (2016): S17-22. doi:10.4103/2231-0762.181162 ↩︎
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