x-pur opti-rinse bottles

Anti-gingivitis & anti-caries

500ml bottles

  • 0.05% Sodium Fluoride - Mint Flavour
  • 0.05% Sodium Fluoride - Grape Flavour
  • 0.2% Sodium Fluoride - Mint Flavour

1 litre bottles

  • 0.05% Sodium Fluoride - Grape Flavour
  • 0.2% Sodium Fluoride - Mint Flavour

4 litre bottle

  • 0.05% Sodium Fluoride - Mint Flavour


What is X-PUR Opti-Rinse Plus?

We are happy to present you a new, enhanced version of the #1 high strength sodium fluoride home-care rinse recommended by Canadian dental professionals: X-PUR Opti-Rinse Plus.

Patented and Unique Formulation
X-PUR Opti-Rinse Plus unique formulation includes Citrox®, which is a natural bioflavonoid complex. Apart from being all-natural, organic and hypoallergenic, Citrox® is very effective at killing bacteria and viruses at very low concentrations. It is a unique plant-based and patented antimicrobial bioflavonoid complex offering a powerful antimicrobial, antioxidant, antifungal, antiviral and anti-inflammatory effect. Citrox® is biodegradable, safe to handle, eco-friendly, alcohol-free, does not contain synthetic fragrances or colourants, and is also free of GMO, petrochemicals and allergenic substances.

Health Canada Indication: Helps Prevent Plaque & Gingivitis
X-PUR Opti-Rinse Plus is not only a solution in your caries management protocol, but also for your periodontal patients. Tackling gingivitis in a profond way!

A Larger Bottle for the Same Price
The second enhancement includes an increase in the bottle size. The X-PUR Opti-Rinse Plus now comes in a 500ml bottle compared to a 473ml one, and for the same price!

A New Mint Flavour for the 0.05% Concentration
X-PUR Opti-Rinse Plus will now be offered in a delicious mint flavour specifically designed for the particular taste of adult patients.


Antimicrobial, Antiviral & Antifungal
This plant-based, patented specific complex of bioflavonoids binds with bacterial cell walls to affect extracellular and soluble proteins through hydrogen bonding which the bacteria and viruses need to survive.


Reduces Cariogenic Bacteria Load
Bacteria that cause tooth decay are not able to metabolize xylitol, resulting in an absence of lactic acid and polysaccharide production.


Against Gingivitis
Broad-spectrum antimicrobial agent that acts by penetrating the cell membrane, causing cell components to leak, which eventually leads to cell death.


Remineralizes tooth enamel, protect against caries
The fluoride ion binds with the calcium ion to form calcium fluoride, adding to the hydroxyapatite, thus making the teeth more resistant to acid dissolution.


  • Proven equivalent in anti-microbial potency as Chlorhexidine oral rinse without the side effects
  • Antimicrobial, antiviral and antifungal
  • Anti-caries - helps to remineralize tooth enamel
  • Efficient, multi-purpose, evidence-based oral rinse
  • Alcohol-free
  • Neutral pH
  • Sweetened with 10% xylitol for a delightful and refreshing taste
  • Unique patented formulation with Citrox®: specific antibacterial bioflavonoid complex


  • Anti-caries
  • Helps to prevent / reduce plaque and gingivitis
  • Helps to remineralize dental enamel (which helps against xerostomia)
0.05% divider


  • Grape
  • Mint


Medicinal Ingredient
  • 0.05% Sodium Fluoride (225 ppm F)

Non-Medicinal Ingredients
Purified water, xylitol, glycerin, poloxamer 407, grape flavour, sodium phosphate, cetylpyridinium chloride, benzoic acid, mint flavour, red 40, bioflavonoids.



Clinical Uses

  • Geriatrics
  • Good oral hygiene
  • Orthodontics
  • Pediatrics
  • Tooth sensitivity
  • Xerostomia

Directions for use

Adults and children aged 6 years and older
Once a day

  1. Rinse with 10 ml for 1 minute. Expectorate.
  2. Do not eat, drink or rinse for 30 minutes.

Children under 6 years of age
Consult a dental professional.

0.2% divider


  • Mint


Medicinal Ingredients
  • 0.2% Sodium Fluoride (905 ppm F)

Non-Medicinal Ingredients
Purified water, xylitol, glycerin, mint flavour, poloxamer 407, sodium phosphate, cetylpyridinium chloride, benzoic acid, tartrazine, blue 1, bioflavonoids.



Clinical Uses

  • Geriatrics
  • Good oral hygiene
  • Orthodontics
  • Pediatrics
  • Tooth sensitivity
  • Xerostomia

Directions for use

Adults and children aged 6 years and older

REGULAR USE Once a week

  1. Rinse with 10 ml for 1 minute. Expectorate.
  2. Do not eat, drink or rinse for 30 minutes.

Use once daily for 1 month or until bottle is finished, by the recommendation of a dental professional.2, 3

Children under 6 years of age
Consult a dental professional.


Antimicrobial activity, in-vitro biocompatibility and anti-inflammatory property of cetylpyridinium chloride-based mouthwash containing sodium fluoride and Xylitol (X-PUR) compared to chlorhexidine

Chlorhexidine 0.12%3 (Control group) X-PUR Opti-Rinse 0.05% X-PUR Opti-Rinse 0.2%
Killing of bacteria responsible for gingivitis (P. Gingivalis) 99.9% ± 0.0% 99.9% ± 0.0% 99.9% ± 0.0%
Killing of bacteria responsible for rampant cavities (S. Sobrinus) 83.7% ± 0.3% 87.5% ± 0.5% 87.5% ± 1.7%
Killing of bacteria in biofilm responsible for cavities (S. Mutans) 68% ± 1.4% 96.7% ± 0.4% 96.4% ± 0.2%
Prescription Yes No No
May cause permanent tooth discolouration Yes No No
Taste altering Yes No No
Calculus formation Yes No No
Oral mucosa desquamation / irritation Yes No No

What is CITROX®, and how does it work against infection in your patients’ mouths?

Research is starting to reveal the potential of mouthwashing procedures as an additional protection against viral and bacterial infections. Citrox® is one of the key ingredients of gargling solutions that helps fight them. But what is it really, and how does it work?

Orange in hand

Keeping the mouths of your patients free from infection affects not only their oral health, but also has long-term effects on their general, long-term well-being. While not meant as primary means of fighting infection, Citrox® is an important ingredient in several mouthwash solutions and provides additional protection against bacteria and viruses when it’s needed most, such as after surgery or during epidemics.

What is Citrox®?

Citrox® is a natural combination of organic acids, and bioflavonoids derived from bitter oranges. It has been designed to serve as a powerful antimicrobial, antiviral and antifungal agent.

Slowly proving itself as an important ingredient in efficient mouthwash solutions, we believe that Citrox®, together with cyclodextrins, will play a crucial role in the future of oral healthcare. Health starts in the mouth, and using mouthwashes to protect the mucous membranes against harm can help lower the risk of your patients becoming infected and developing a range of serious non-communicable diseases and conditions.

How does Citrox® work against bacteria and viruses?

The effect of Citrox® largely comes down to the flavonoids in it.

The bioflavonoids bind to bacteria’s receptor sites, blocking the passages that bacteria need for feeding and emptying. Unable to sustain these processes, the bacteria essentially drown, killed by the flavonoid.

Orange in hand

Furthermore, unlike some other compounds used for infection control in dentistry, Citrox® is non-toxic, non-corrosive, non-carcinogenic and non-allergenic. It doesn’t stain teeth or alter food flavor, and it’s dermatologically tested, biodegradable, safe and eco-friendly.

When can Citrox® help?

Citrox® has been designed as an ingredient in oral care products, enhancing their healing and protective effects. Citrox®-enabled mouth rinses can help especially:

  • Before and after oral surgery
  • Against periodontal disease
  • Against candidal infections
  • Combined with other ingredients (such as chlorhexidine), serving as an important additional protection

In these situations, Citrox®-containing oral health products can form part of the prophylactic measures that you can recommend to your patients to help them keep their oral mucosa protected, helping reduce risk of infection.

In the end, it’s complex care of the mucous tissues what helps protect the patient from becoming infected. And with mouth rinse procedures being fast and easy to apply, we believe that in the future, they will become even more important for keeping your patients healthy – especially in situations when the mucosa is exposed to physical stress such as after surgical procedures or during viral epidemics.


Antimicrobial activity of Citrox (R) bioflavonoid preparations against oral microorganisms


I have lousy teeth. This product, along with avoiding added sugars in food, keeps my dental problems to a minimum. For people like me you need to get the .05. Fluoride.

- R. Caron, a patient

I learned about this mouthwash at my dentist after a really bad spate of cavities, crowns, and an extraction. I use it every night last thing and then do not wash out my mouth or eat anything. My dental appointments are having much better results. This is a must-have product for me now.

- Guitarwoman, a patient

Featured Publications


  1. S. J. Hooper, M. A. O. Lewis, M. J. Wilson and D. W. Williams. Antimicrobial activity of Citrox® bioflavonoid preparations against oral microorganisms, British Dental Journal, 2011.
  2. Genevieve Lebel et alii. Groupe de Recherche en Écologie Buccale (GREB). Faculté de Médecine Dentaire. Université Laval, Québec, Québec, Canada. Article is awaiting publication.
  3. Université Laval, Québec, 2018. [LINK]
  4. Featherstone, J.D.B. A Randomized Clinical Trial of Anticaries Therapies Targeted according to Risk Assessment (Caries Management by Risk Assessment), Caries Research, 2012;46 :118-119. [LINK]
  5. Featherstone, J.D. The Role of Remineralizing and Anticaries Agent in Caries Management, Advances in Dental Research, August 16 2012, p. 28-31.
  6. Bacteria blamed for rapid tooth decay open wide genomically. Genetic Engireening & Biotechnology News, June 2018. [LINK]
  7. Naito M, Hirakawa H, Yamashita A, et al. (August 2008). Determination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Genomic Comparison with Strain W83 Revealed Extensive Genome Rearrangements in P. gingivalis. DNA Res. 15 (4): 215–25.
  8. J Oral Maxillofac Pathol. 2017 May-Aug; 21(2): 316.


Consult MSDS