gengigel prof box

Hyaluronic acid professional syringes

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Natural alternative to locally applied antibiotics

Mechanism of action

High molecular weight hyaluronic acid (HA) is a natural physiological constituent of connective tissue. It plays a critical role in the collagen-making process. Made up mostly of collagen, it is one of the major components of the human body. HA is the most abundant high molecular weight glycosaminoglycan of healthy soft periodontal tissues.4 It is active in tissue regeneration and influences the migration of fibroblasts and fibrinogenesis, thus making the healing of tissue easier. It performs 3 synergistic effects: anti-inflammatory, accelerates the healing process and provides a protective barrier.

Contributing to the barrier function and tensile strength of the periodontal ligament, HA is essential for healthy gingival tissues. In the initial stage of inflammation and periodontal disease, tissue’s requirement for HA increases by 200%, demonstrating its central role in regulating cell turnover and optimizing tissue regeneration. When lacking HA, healing will be delayed and inflammation will continue

Indications

• Anti-inflammatory effect
• In conjunction with scaling and root planing:
      • Reduces bleeding in patients with chronic periodontitis
      • Effective against gingival pockets
• Promotes and accelerates gingival re-attachment after surgical trauma

3 synergistic effects of gengigel: reparative, anti-inflammatory and proctective

Benefits

• Can be applied by dental hygienists
• Cost-effective
• Pre-filled syringes are individually blister-packed to ensure the integrity of the product
• Syringes supplied with 4 long flexible tips to ensure better application of the product to the points which are most difficult to reach
• Tip secured to the syringe with the simple, immediately understandable luer-lock system
• Odourless and colourless

Ingredients

Medicinal Ingredients
0.8 % Hyaluronic acid

Kit includes

• 4 pre-filled 1 ml syringes
• 4 disposable plastic tips

NPN

80060902

Directions for use

Adults
One application (1ml) per appointment
1. Remove the screw cap from the syringe.
2. Attach the disposable tip to the syringe.
3. Apply Gengigel to the base of the periodontal pockets.

Other clinical use

Oral lesions

gengigel prof syringes

Medicinal Ingredients

High molecular weight hyaluronic acid (HA) is a natural physiological constituent of connective tissues. It is the most abundant high molecular weight glycosaminoglycan of healthy soft periodontal tissues.4

gengigel bottle

0.2% hyaluronic acid topical gel

Get your pads & samples » Learn More »

Testimonials

... Client was so happy! Excellent result! I recommended a 3 month hygiene appointment to check the area and at that time I will take 1 PA for comparison of the PA that was taken in September 2016. [Read more »]

- Christine Chore, RDH, PID, BSc (DH), Floss-On & Smile-On

References

  1. Bansal J, Kedige SD, Anand S., Hyaluronic acid: A promising mediator for periodontal regeneration, Indian J Dent Res 2010;21:575-578. [download]
  2. Rahemtulla F., Proteoglycans of oral tissues, Crit Rev Oral Biol Med 1992;3:135-162. [abstract]
  3. Salazar Monsalve L, Rodríguez Lara V, González Villalva AE. En Fortoul T, Castell A., Histología y biología celular, McGrawHill México, 1ª ed. 2010. Capítulo 5: Tejidos. [link]
  4. Sukumar S, Drízhal I., Hyaluronic acid and periodontitis, Acta Medica (Hradec Kralove) 2007;50:225-258. [link]
  5. Weigel PH, Hascall VC, Tammi M., Hyaluronan Synthases, J Biol Chem 1997;272(22):13997-14000.[abstract]
  6. Hascall VC, Laurent TC., Hialuronan: Structure and physical properties, 1997. [link]
  7. Silvera Arenas LA, Barrios de Zurbarán C., La matriz extracelular: el ecosistema de la célula Salud Uninorte. Barranquilla 2002;16:9-18. [link]
  8. Choukroun J, Diss A, Simonpieri A et al., Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part IV: Clinical effects on tissue healing Med Oral Pathol Oral Radiol Endod 2006; 101:E56-E60. [link]
  9. Weigel PH, Fuller GM, Le-Boeuf RD., A model for the role of hyaluronic acid and fibrin in the early events during the inflammatory response and wound healing, J Theor Biol 1986;119(2):219-234. [link]
  10. Sakasi T, Watanabe C., Stimulation of osteoinduction in bone wound healing by high-molecular hyaluronic acid, Bone 1995;16:9-15. [link]
  11. Pirnazar P, Wolinsky L, Nachnani S et al., Bacteriostatic effects of hyaluronic acid, J Periodontol 1999;70:370-374. [download]
  12. Sakai A, Akifusa S, Itano N et al., Potential role of high molecular weight hyaluronan in the anti-Candida activity of human oral epithelial cells, Med Mycil Feb 2007;45(1):73-79. [link]