With silver diamine fluoride (SDF), it is now possible to reverse and arrest the cariogenic process, even if cavitations are present. It results from a combination of ingredients that form silver-protein conjugates in decayed surfaces. The silver ions act directly against bacteria in lesions by breaking membranes and re-acidification13, 14, while the fluoride ion acts to prevent further demineralization. Hydroxyapatite and fluoroapatite then form on the exposed organic matrix, along with the presence of silver chloride and metallic silver.5
Video credit: Oasis Discussions
Are you someone looking to know which dental office in your area can provide you with Adavantage Arrest? Click on the button below to see a list of dental offices where silver diamine fluoride is a treatment option.
• Cost-efficient :
± $0.88 (1 drop) to ± $1.76 (2 drops) for 5 surfaces*
• 8ml bottle = 250 drops
• Each drop = Up to 5 surfaces
• Colourless and odourless
• Dental hygienists can apply it
• Increases resistance to acid dissolution and enzymatic digestion11
*Based on an 8ml bottle at 220$
• Increases in mineral density and hardness while the lesion depth decreases5
• No post-treatment limitations
• Outperforms other anti-caries treatments in killing cariogenic bacteria15
• Quick application in less than 5 minutes
• User-friendly, no need for:
• Air or water
38% Silver Diamine Fluoride
(25% Silver, 5.5% Fluoride, 8% Ammonia)
Adults and children 3 years and older
Once every 6 months
Precautions before use
1. Isolate the affected area of the tooth. Protect patient’s eyes. Minimize contact with gingival tissues.
2. If accidental contact occurs, thoroughly wash the area with water, saline solution or 3% hydrogen peroxide.
1. Clean and dry the affected tooth surface.
2. For up to 5 surfaces, dispense 1-2 drop(s) of solution into a disposable dappen dish. Transfer material directly to the tooth surface with an applicator and allow to seal for a few seconds.
3. Excess can be wiped or rinsed away after application.
4. If needed, 1 or 2 reapplications may be administered at intervals of one week.
Consult a health care practitioner prior to use if you are pregnant or breastfeeding.
Staining is an indicator of antimicrobial effectiveness.
The functional indicator of effectiveness is when the silver oxide is bound to the diseased collagen and intrinsic pigmentation of a carious lesion occurs. These oxides don’t polish away because the blackened lesion retains its dark color for a long period, which is why the antimicrobial effect is long lasting.
SDF stains demineralized areas and soft-tissues. Stains can be reduced by gentle polishing with tincture of weak iodine solution or by being covered with Glass Ionomer.
The staining is not immediate but will be noticed within hours. It will be limited to direct areas of contact. For soft-tissue, it will fade over a period of 24 to 72 hours.
SDF does not stain sound or healthy enamel or dentin.
SDF stains clothing, counters, floors and instruments.
Black mat is an indicator that the lesion is static.
1870-1912: SDF IS USED FOR 80 YEARS AS A CARIES-ARRESTING AGENT IN ASIA
Ohaguro, a custom of dyeing one's teeth black, was practiced in Japan and other countries. It was also beneficial, as it prevented tooth decay.
2014: ADVANTAGE ARRESTTM IS CLEARED BY THE U.S. FDA
Advantage Arrest is cleared by the U.S. Food & Drug Administration (FDA) for dentinal hypersensitivity.
2015: ADVANTAGE ARRESTTM IS AVAILABLE IN THE U.S.
Advantage Arrest is commercially available in the United States through Elevate Oral Care, LLC. Since then, it has been used extensively by oral health professionals in the U.S., off-label for the arrest of tooth decay.
2016: GRANTED THE FDA BREAKTHROUGH THERAPY DESIGNATION FOR THE ARREST OF TOOTH DECAY
Advantage Arrest is granted the 1st Breakthrough Therapy Designation by the FDA for an oral care product. This designation represents the FDA’S effort to address an unmet, serious, life-threatening medical need where there is no available therapy and to expedite the review of such products. The designation was granted based on the FDA review of 10 worldwide randomized clinical trials evaluating silver diamine fluoride for caries arrest in children aged 3-9 or adults aged 60-89. Collectively these trials involved 1,500 subjects who were monitored for 1-3 years.
2016: THE NEW YORK TIMES PUBLISHES AN ARTICLE ON SDF
Advantage Arrest is the subject of hundreds of lectures, online posts and articles. It is featured on major consumer media outlets including the New York Times, which published a whole story entitled “A Cavity-Fighting Liquid Lets Kids Avoid Dentists’ Drills”.
2017: ADVANTAGE ARRESTTM IS APPROVED BY HEALTH CANADA
Advantage Arrest is granted the Health Canada indication of an anti-caries agent.
Just got back from the ASM (2017) last week where I ordered my first bottle of Advantage Arrest from Oral Science. By far my favourite company for quality products. This product enables you to arrest those "suspicious lesions". I can't see how this wouldn't be beneficial for every IRDH!
- Heather Wolframe, owner of Go Smile practice